Talphera, Inc..
TLPH.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products
Talphera, Inc. is a biopharmaceutical company focused on discovering, developing, and commercializing novel therapies for the treatment of liver diseases. Their primary focus is on developing treatments for nonalcoholic steatohepatitis (NASH) and other related liver conditions. The company's researc...Show More
Better Health for All
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Talphera's lead candidate, Niyad™ (nafamostat mesylate), aims to improve the standard of care for patients undergoing renal replacement therapy (RRT) and is being investigated for potential antiviral and anti-inflammatory applications, indicating substantial health benefits.
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The company divested its acute pain product, DSUVIA, in 2023, signifying a transition to health-positive offerings.
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Nafamostat has an established safety record from over 30 years of use in Japan and South Korea, and its current U.S. trial is designed to assess safety.
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However, the company's former acute pain products (ARX-04 and Zalviso) were projected to have a U.S. market price of $20 per unit and 15 euro per unit in Europe, which is 5-6 times the estimated production cost of $3-4 per unit.
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The company discusses opioid abuse and diversion related to its former acute pain products but does not detail specific mitigation efforts.
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While clinical trial protocols and endpoints are mentioned, and the NEPHRO CRRT study has central IRB approval, there is no comprehensive information on ethical frameworks or diversity in trials.
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The company's focus on developing new therapies for medically supervised settings indicates a significant investment in health innovation, with clinical trials and pipeline products like Niyad™ and LTX-608™.
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Fair Money & Economic Opportunity
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No evidence available to assess Talphera, Inc. on Fair Money & Economic Opportunity.
Fair Pay & Worker Respect
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No evidence available to assess Talphera, Inc. on Fair Pay & Worker Respect.
Fair Trade & Ethical Sourcing
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No evidence available to assess Talphera, Inc. on Fair Trade & Ethical Sourcing.
Honest & Fair Business
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No evidence available to assess Talphera, Inc. on Honest & Fair Business.
Kind to Animals
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Talphera, Inc. conducts pre-clinical studies on animals to assess product safety, leading to its inclusion on a 'use of animals' list by crueltyfreeinvesting.org.
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No specific data is provided regarding the company's use of alternative testing methods, humane certifications, wildlife conservation efforts, ethical input substitution, supplier audits, cage-free sourcing, animal testing volume, innovation investment in animal-free technologies, animal agriculture ethics, animal-free R&D collaboration, or public policy engagement on animal welfare.
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No War, No Weapons
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No specific, concrete data points were found in the provided articles for Talphera, Inc. (TLPH.US) regarding its involvement with arms manufacturing, military contracts, conflict facilitation, or peacebuilding initiatives. Several articles explicitly state that sustainability data is unavailable for TLPH or that the content is not relevant to TLPH.US or the 'No War, No Weapons' value. While one article mentions Talphera, Inc., it explicitly states that it does not contain data relevant to the 'No War, No Weapons' value.
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Planet-Friendly Business
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No evidence available to assess Talphera, Inc. on Planet-Friendly Business.
Respect for Cultures & Communities
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No evidence available to assess Talphera, Inc. on Respect for Cultures & Communities.
Safe & Smart Tech
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No evidence available to assess Talphera, Inc. on Safe & Smart Tech.
Zero Waste & Sustainable Products
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No evidence available to assess Talphera, Inc. on Zero Waste & Sustainable Products.