MASHINIi

89bio, Inc..

ETNB.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

89bio, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapies for liver and cardio-metabolic diseases. The company's lead product candidate is pegozafermin, a specifically engineered glycoPEGylated fibroblast growth factor 21 (FGF2...Show More

Ethical Profile

Mixed.

89bio, Inc. holds a mixed ethical rating. Developing therapies like pegozafermin for serious unmet needs (MASH, SHTG) aligns with improving health. However, a potential tension exists with affordable access, contingent on future drug pricing. 89bio likely conducts standard animal testing during preclinical phases; while commitment to the 3Rs (reduce, refine, replace) is noted, top animal welfare scores require full avoidance. Lab operations contribute to environmental impacts via energy use and hazardous waste. Ethical conduct centers on clinical trial integrity and transparent communication; no major breaches reported.

Value Scores

Better Health for All0
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals-40
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

0

No evidence available to assess 89bio, Inc. on Better Health for All.

Fair Money & Economic Opportunity

0

No evidence available to assess 89bio, Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

No evidence available to assess 89bio, Inc. on Fair Pay & Worker Respect.

Fair Trade & Ethical Sourcing

0

No information was found in the provided articles regarding 89bio, Inc.'s fair trade certifications, supply chain audit frequency, incidents of forced or child labor, traceability coverage, remediation speed for violations, ethical clause coverage in supplier contracts, share of spend on high-risk materials, or supplier diversity spend.

1

Honest & Fair Business

0

No evidence available to assess 89bio, Inc. on Honest & Fair Business.

Kind to Animals

-40

89bio, Inc. has conducted seven animal studies for its drug candidate BIO89-100, involving mice and non-human primates.

1
Specifically, 50 mice were used in a diet-induced NASH study, and 24 spontaneously diabetic obese cynomolgus monkeys were used in another study.
2
The company states it is in compliance with animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines.
3
Preclinical studies of BIO89-100 used spontaneously diabetic obese cynomolgus monkeys and mouse models of NASH.
4

No War, No Weapons

0

No evidence available to assess 89bio, Inc. on No War, No Weapons.

Planet-Friendly Business

0

No evidence available to assess 89bio, Inc. on Planet-Friendly Business.

Respect for Cultures & Communities

0

No specific, concrete data points were found in the provided articles to assess 89bio, Inc. against any of the KPIs for the 'Respect for Cultures & Communities' ethical value. The articles primarily focus on company overview, leadership, clinical trials, and general ESG risk ratings without detailing community engagement, cultural impact protocols, or related metrics.

Safe & Smart Tech

0

No evidence available to assess 89bio, Inc. on Safe & Smart Tech.

Zero Waste & Sustainable Products

0

No evidence available to assess 89bio, Inc. on Zero Waste & Sustainable Products.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.