MASHINIi

SciSparc Ltd..

SPRC.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

SciSparc Ltd. is a specialty clinical-stage pharmaceutical company, focused on the development of therapies to treat disorders of the central nervous system. The company's lead drug candidate is SCI-110, which is being developed for the treatment of Tourette's Syndrome, Alzheimer's disease, and obst...Show More

Ethical Profile

Mixed.

SciSparc Ltd. presents a mixed ethical picture. The company faced a Nasdaq suspension and delisting in 2020 due to equity requirements, undergoing economic rehabilitation proceedings and replacing its board of directors. It was relisted in 2021, now featuring independent audits and a majority independent board. Positively, its SCI-110 Tourette's trial showed a 21% average tic reduction, with almost 40% of patients experiencing over a 25% reduction. SciSparc also develops therapies for autism and pain. Environmentally, the company reduced Scope 1, 2, and 3 emissions to 3,450 metric tons in 2023 (from 4,460 in 2022), achieved a 76% waste diversion rate in research, and invested $2.3 million in green infrastructure. However, critics point to a DitchCarbon.com score of 18, lower than 78% of the industry.

Value Scores

Better Health for All10
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business40
-100100
Kind to Animals-40
-100100
No War, No Weapons0
-100100
Planet-Friendly Business-20
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

10

SciSparc Ltd. is a clinical-stage pharmaceutical company entirely devoted to developing therapies for central nervous system disorders, with 100% of its drug candidates aimed at health improvement.

1
Phase IIa trials for SCI-110 showed an average 21% tic reduction in Tourette Syndrome patients and a 23% reduction in agitation symptoms in elderly Alzheimer's patients, with patients free of delirium, oversedation, hypotension, or falls.
2
The company is developing SCI-110 for Tourette Syndrome, Alzheimer's disease and agitation, and SCI-210 for autism spectrum disorder, all of which address mental health needs.
3
The company's SCI-110 aims to decrease dosage requirements, side effects, and adverse events compared to Dronabinol, a synthetic THC.
4
Clinical trials for SCI-210 for autism spectrum disorder and SCI-110 for Tourette Syndrome are double-blind, randomized, and placebo-controlled, and have secured Institutional Review Board approvals for all sites.
5
However, the company's clinical trials for SCI-210 and SCI-110 target specific age groups (children aged 5-18 with ASD, adults aged 18-65 with Tourette Syndrome, and elderly Alzheimer's patients), which represents a limited reach to vulnerable populations.
6
Furthermore, the renewal of approval for a clinical trial was for only 30 days, pending final approval from the Israeli police department, indicating potential regulatory scrutiny or delays.
7
The company also relies on forward-looking statements, which involve risks and uncertainties detailed in SEC filings.
8

Fair Money & Economic Opportunity

0

No evidence available to assess SciSparc Ltd. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

No evidence available to assess SciSparc Ltd. on Fair Pay & Worker Respect.

Fair Trade & Ethical Sourcing

0

No evidence available to assess SciSparc Ltd. on Fair Trade & Ethical Sourcing.

Honest & Fair Business

40

SciSparc Ltd. has all its subsidiaries covered by an independent external audit, which is conducted by Kost Forer Gabbay & Kasierer (EY Global).

1
The company also has a Code of Ethics and Conduct document available.
2
However, SciSparc received a notification from Nasdaq on January 12, 2026, for non-compliance with the minimum stockholders' equity requirement, reporting approximately $(81,000) as of June 30, 2025, against a $2.5 million requirement.
3
This follows a previous delisting notice in July 2024 for not meeting the minimum bid price requirement, which was resolved by a 1-for-21 reverse share split in July 2025.
4

Kind to Animals

-40

SciSparc Ltd. is listed as a company that uses animal testing.

1
There is no evidence of a formal policy to restrict, reduce, or ban animal testing. A specific pre-clinical trial conducted by the company used 84 mice.
2
While this is for a single trial, it is the only concrete volume provided, falling below the 1,000 animals per year threshold.

No War, No Weapons

0

No evidence available to assess SciSparc Ltd. on No War, No Weapons.

Planet-Friendly Business

-20

In 2023, the company's total Scope 1, 2, and 3 greenhouse-gas emissions were 3,450 metric tons, representing a 22.64% reduction from the 2022 baseline of 4,460 metric tons.

1
The waste diversion rate for research facility waste was 76% in 2023, an increase from 62% in 2022.
2
The company maintained a strong regulatory compliance record with a 92% pass rate on annual compliance audits by the Israel Medical Devices and Diagnostic Regulatory Division.
3

Respect for Cultures & Communities

0

No evidence available to assess SciSparc Ltd. on Respect for Cultures & Communities.

Safe & Smart Tech

0

The company's privacy policy states that users can request access, update, or removal of their data, and that data is retained only as needed for specified purposes.

1
The policy also mentions compliance with applicable laws.
2
However, no further specific details or quantitative evidence are provided regarding the comprehensiveness of user controls, specific data retention periods, or the effectiveness of regulatory compliance.
3

Zero Waste & Sustainable Products

0

No evidence available to assess SciSparc Ltd. on Zero Waste & Sustainable Products.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.