Sage Therapeutics, Inc..
SAGE.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products
Sage Therapeutics, Inc. is a biopharmaceutical company committed to developing and commercializing novel medicines to treat brain disorders. The company focuses on developing therapies for central nervous system (CNS) disorders, including depression, postpartum depression, anxiety, and neurological ...Show More
Better Health for All
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Sage Therapeutics' core business is developing and marketing FDA-approved treatments for brain disorders, including postpartum depression, with a pipeline for Huntington's and Alzheimer's disease.
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Clinical trials for Zurzuvae show 57-72% of women experienced at least a 50% reduction in depressive symptoms, with improvement in as little as three days.
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The company invested over $350 million in R&D in 2023, representing over 50% of operating costs.
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Zurzuvae is covered for approximately 95% of insured commercial and Medicaid patients by the three largest pharmacy benefit managers as of December 2024, and Sage offers a Savings Card Program that may reduce copays to $0 for eligible commercially insured patients and copay assistance for uninsured patients.
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However, the wholesale acquisition cost of Zurzuvae is $15,900 for a 14-day course, which is significantly higher than generic SSRIs costing less than $20 per month.
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The drug's label includes a prominent warning about potential hazardous activities after use due to its depressant effect, and it is classified as a Schedule IV drug by the DEA.
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The company provides monthly cybersecurity and privacy training to employees and has a robust cybersecurity program, but specific data protection standards or transparency levels are not detailed.
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Clinical trial processes were reviewed in 2022 to improve diversity and inclusivity.
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Fair Money & Economic Opportunity
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Sage Therapeutics is a biopharmaceutical company focused on developing and commercializing medicines. Its core business does not involve lending, deposit services, or other financial products for consumers. Therefore, KPIs related to financial services, such as underserved client share, pricing fairness, exploitative fee exposure, inclusion initiatives, data accessibility, fair lending compliance, wealth building outcomes, profit reinvestment in community finance, debt burden ratio, geographic inclusion, and product simplicity, are not applicable to its operations. While the company provides patient assistance programs and educational resources, these do not align with the specific financial services definitions of the KPIs in this rubric.
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Fair Pay & Worker Respect
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No specific, concrete data points for Sage Therapeutics, Inc. (SAGE.US) relevant to the Fair Pay & Worker Respect value were found in the provided articles. and contained no relevant information or were inaccessible. explicitly states that no quantitative data specific to SAGE.US is available, and the metrics provided in that article pertain to a different company, "OneKreate".
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Fair Trade & Ethical Sourcing
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No quantitative data or specific evidence related to fair trade and ethical sourcing practices, such as fair-trade certification share, audit frequency, forced/child labor incidents, supply chain traceability, remediation speed, ethical clause coverage in contracts, materials risk index, or supplier diversity spend, was found in the provided articles.
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The documents primarily outline policies, codes of conduct, and general commitments without reporting on specific performance metrics or outcomes.
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Honest & Fair Business
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Sage Therapeutics, Inc. provides a confidential and anonymous financial concern hotline for complaints regarding accounting, internal accounting controls, or auditing matters.
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Messages sent through this hotline are encrypted and delivered directly to the Audit Committee.
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Users receive a 14 to 16-digit code to access the status of their message.
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However, there is no evidence provided regarding independent investigation processes for these reports.
Kind to Animals
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No specific, concrete evidence was found in the provided articles to assess Sage Therapeutics, Inc. against any of the 'Kind to Animals' KPIs. The articles did not contain factual data points regarding animal testing volumes, policies, alternative testing usage, cruelty-free certifications, humane certifications, ethical input substitution, supplier audits, cage-free sourcing, wildlife conservation impact, R&D investment in animal-free technologies, animal agriculture ethics, animal-free R&D collaboration, or public policy engagement related to animal welfare.
No War, No Weapons
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No evidence available to assess Sage Therapeutics, Inc. on No War, No Weapons.
Planet-Friendly Business
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Sage Therapeutics, Inc. reported total Scope 1, 2, and 3 emissions of 4,230 metric tons CO2e in 2022.
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The company achieved a 17.6% reduction in greenhouse gas emissions in 2022.
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In the same year, 22.3% of its operational energy was sourced from renewables, with a projected increase to 28.5% in 2023.
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The company conducted 6 environmental impact assessments.
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Respect for Cultures & Communities
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Sage awards grants to at least 10 eligible urban Native health and human service organizations and urban Indian organizations, indicating formal partnerships.
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FPIC processes are not applicable to the company's operations, as its grant program does not focus on projects impacting Indigenous lands or resources.
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While the grant program targets organizations with a majority of urban Indians in leadership, there is no evidence of community representation on Sage's own governance or advisory bodies.
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The program encourages the use of American Indian and Alaska Native traditional, cultural, and regional knowledge, but there is no specific evidence of Sage's own reinvestment in cultural or linguistic preservation programs.
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Safe & Smart Tech
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No evidence available to assess Sage Therapeutics, Inc. on Safe & Smart Tech.
Zero Waste & Sustainable Products
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No specific, quantitative data was provided in the articles to assess Sage Therapeutics, Inc. against the 'Zero Waste & Sustainable Products' ethical value. Information regarding waste diversion rates, product recyclability, packaging sustainability percentages, recycled content, single-use plastic reduction, take-back program coverage, circular design principles, waste audit frequency, zero-waste certifications, waste disposal violations, material efficiency, packaging-to-product ratio, waste reduction targets, supplier waste requirements, and customer waste education was not available.
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While the company maintains a recycling and composting program in offices and sources compostable products for kitchenware, these details lack the quantitative metrics required by the rubric for scoring.
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