MASHINIi

PureTech Health plc.

PRTC.US | Research and experimental development on natural sciences and engineering

PureTech Health plc is a biotherapeutics company dedicated to discovering, developing and commercializing highly differentiated medicines for devastating diseases, including intractable cancers, lymphatic and gastrointestinal diseases, and brain and immune disorders. The Company has created a pipeli...Show More

Ethical Profile

Mixed.

PureTech Health plc focuses on developing pharmaceutical solutions for devastating diseases like cancer, IPF, and depression, alongside novel diagnostic technologies, aligning with 'Better Health for All.' However, as a biotechnology company, its drug development inherently relies on animal testing, which critics point to as conflicting with 'Kind to Animals.' While 50% of its C-suite is female, reports suggest insufficient public data on key metrics for fair pay, worker respect, ethical sourcing, and environmental impact. Information on data protection, anti-corruption, and community engagement is also largely unavailable.

Value Scores

Better Health for All0
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect-30
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business-40
-100100
Kind to Animals-40
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products-60
-100100

Better Health for All

0

No evidence available to assess PureTech Health plc on Better Health for All.

Fair Money & Economic Opportunity

0

No evidence available to assess PureTech Health plc on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

-30

None of the company's employees are subject to collective bargaining agreements or represented by a trade or labor union.

1
The voluntary employee turnover rate was 30.62% in 2022, following 25% in 2021.
2
An employee engagement survey was conducted in 2021, but results were not explicitly quantified in the annual report.
3
However, Glassdoor reviews indicate an average employee rating of 3.2 out of 5 stars.
4
The company reported no substantiated labor-law or human-rights violations.
5

Fair Trade & Ethical Sourcing

0

No specific, concrete data points were found in the provided articles regarding PureTech Health plc's fair trade and ethical sourcing practices.

1
Therefore, no KPIs could be scored against the rubric.

Honest & Fair Business

-40

The company has a Whistleblowing policy and a Bribery prevention policy, with the board approving procedures for fraud detection and bribery prevention, aligning with the UK Bribery Act 2010.

1
However, there is no evidence of training frequency or effectiveness metrics for the anti-corruption policy. The board considers and authorizes directors' conflicts of interest.
2
At the June 16, 2025 Annual General Meeting, more than 20% of votes were cast against the re-election of Ms. Mazumdar-Shaw as a Director and against the Directors’ Remuneration Report.
3
Following this, the company engaged with shareholders representing nearly 50% of issued share capital during July 2025.
4

Kind to Animals

-40

PureTech Health plc uses animal models for preclinical testing, including large animal and non-human primate models for LYT-310.

1
The company also develops LYT-100 for medical countermeasures under the FDA Animal Rule, which allows for drug approval based on animal models when human efficacy studies are not feasible.
2
Between 2020 and 2022, the company used 10,000 to 15,000 animals annually in testing. PureTech Health is a member of the European Partnership for Alternative Approaches to Animal Testing (EPAA) and the American Association for Laboratory Animal Science (AALAS). The Glyph technology platform, which is part of PureTech's R&D, is based on research from Monash University.
3

No War, No Weapons

0

No evidence available to assess PureTech Health plc on No War, No Weapons.

Planet-Friendly Business

0

No evidence available to assess PureTech Health plc on Planet-Friendly Business.

Respect for Cultures & Communities

0

No specific, quantitative evidence was found in the provided articles regarding PureTech Health plc's performance on any of the KPIs related to the 'Respect for Cultures & Communities' ethical value. The articles discuss other ESG initiatives, such as gender and ethnic diversity in leadership and board positions, and general ESG ratings, but do not provide data on community partnerships, cultural impact assessments, local employment, grievance mechanisms, or any other metrics relevant to this value.

1

Safe & Smart Tech

0

No specific evidence was found in the provided articles regarding PureTech Health plc's (PRTC.US) performance across any of the Safe & Smart Tech KPIs. The articles discuss general industry trends, other companies' data, or general principles of compliance, but do not provide concrete, measurable facts about PRTC.US's data protection, cybersecurity, or AI ethics practices.

Zero Waste & Sustainable Products

-60

PureTech Health plc is not participating in any tracked waste reduction initiatives and has not disclosed any specific waste reduction targets or pledges.

1
No regulatory actions, violations, fines, or compliance issues related to waste disposal are mentioned in the provided articles.
2

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.