MASHINIi

Lipocine Inc..

LPCN.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Lipocine Inc. is a pharmaceutical company focused on the development and commercialization of innovative pharmaceutical products for men's and women's health. The company's primary focus is on developing oral testosterone replacement therapies for hypogonadism, a condition in which the body doesn't ...Show More

Ethical Profile

Mixed.

Lipocine Inc. focuses on developing treatments for significant health needs. Its LPCN 1154 targets rapid relief for postpartum depression, a condition affecting many new mothers. LPCN 1148, with FDA Fast Track designation, shows positive Phase 2 results for sarcopenia and hepatic encephalopathy. The company's FDA-approved TLANDO, an oral testosterone replacement therapy, addresses hypogonadism, though it carries potential cardiovascular risks. Critics point to limited information on price accessibility for these treatments. Furthermore, as a pharmaceutical developer, Lipocine's operations are likely to involve animal testing for drug development and regulatory approval, which inherently conflicts with being "Kind to Animals."

Value Scores

Better Health for All-30
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business-30
-100100
Kind to Animals0
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

-30

Lipocine Inc. is a pharmaceutical company whose entire product portfolio, including FDA-approved TLANDO for hypogonadism and multiple drug candidates in development, is dedicated to addressing various health conditions such as postpartum depression, epilepsy, essential tremor, obesity, liver cirrhosis, and prevention of preterm birth.

1
This indicates a business entirely devoted to health improvement. However, TLANDO carries a Boxed Warning for blood pressure increases and cardiovascular risks, and is a Schedule III controlled substance with abuse potential.
2
The FDA recommended removing the MACE Boxed Warning but requires product-specific blood pressure information, with average systolic BP increases of 4.3-4.8 mmHg observed in a clinical study.
3
While other pipeline products like LPCN 1154, LPCN 2401, and LPCN 1148 have shown favorable safety profiles in trials, the approved product has significant safety concerns.
4
The company's Code of Ethics mandates full, fair, accurate, timely, and understandable disclosures in public filings and requires employees to protect confidential medical information.
5
LPCN 1154 for postpartum depression is designed for at-home treatment, potentially improving access, and targets women aged 15 and older with severe PPD.
6
The company's R&D is focused on developing these innovative products using its proprietary drug delivery technology.
7
LPCN 1107 is a candidate for prevention of preterm birth, and TLANDO requires monitoring of blood pressure, hematocrit, and PSA, indicating some preventative aspects.
8
The company has a Code of Ethics and Business Conduct that applies to all directors, officers, and employees, requiring compliance and training.
9

Fair Money & Economic Opportunity

0

No evidence available to assess Lipocine Inc. on Fair Money & Economic Opportunity.

Fair Pay & Worker Respect

0

No specific, quantitative evidence was found across the provided articles for any of the Key Performance Indicators related to Fair Pay & Worker Respect. Information such as living wage coverage, CEO-to-median pay ratio, collective bargaining share, safety incident rate, pay equity ratio, worker engagement score, turnover rate, labor violation incidents, insecure contract share, or health insurance coverage was not explicitly stated with concrete data points.

1
While some articles mentioned employee reviews or general benefits, they did not provide the specific metrics required by the rubric to assign a score.

Fair Trade & Ethical Sourcing

0

No specific, quantitative evidence regarding fair trade certifications, supplier audit frequency, forced or child labor incidents, supply chain traceability, remediation speed for violations, ethical clause coverage in supplier contracts, share of spend on high-risk materials, or supplier diversity spend was found in the provided articles for Lipocine Inc.

Honest & Fair Business

-30

Lipocine Inc. has a Code of Ethics and Business Conduct that includes a whistleblower policy outlining reporting procedures, anonymous reporting for accounting, internal controls, or auditing matters, and protection against retaliation.

1
However, the policy does not explicitly detail independent investigation processes.
2
The company's annual report summary indicates no financial restatements.
3
A policy prohibiting bribes, kickbacks, and improper payments is in place, but specific details on its enforcement or training frequency are not provided.
4

Kind to Animals

0

While Lipocine Inc. is noted to engage in animal testing,

1
the provided articles do not offer specific quantitative data or detailed policy descriptions for any of the KPIs in the rubric. Therefore, no scores can be assigned.

No War, No Weapons

0

Lipocine Inc. is a biopharmaceutical company focused on developing and commercializing pharmaceutical products.

1
The company's 2023 Form 10-K filing explicitly states that its business is focused on pharmaceuticals, not arms contracts.
2
No evidence was found in any provided article regarding revenue from arms contracts, dual-use technology, sales to embargoed regimes, peacebuilding investment, conflict divestment policy, board oversight of defense activities, export compliance, lobbying, humanitarian procurement, human rights due diligence, Arms Trade Treaty compliance, AI military safeguards, UN Guiding Principles alignment, dual-use screening, surveillance transparency, ethical red lines, zero exposure to controversial weapons, war risk audits, annual conflict partner reviews, defense divestment, conflict minerals, peace tech investment, conflict zone procurement, or ethical red lines compliance rates.
3
The company's Code of Ethics and Business Conduct outlines general ethical practices but does not specifically address weapons or conflict-related red lines.
4

Planet-Friendly Business

0

The provided articles, including financial reports and company profiles, do not contain any specific, concrete data points or mentions related to environmental performance, targets, or initiatives for Lipocine Inc. Information regarding carbon emissions, renewable energy use, water management, waste diversion, green building certifications, supply chain climate transparency, biodiversity efforts, or climate-related financial disclosures is not available.

1

Respect for Cultures & Communities

0

No specific, concrete data points were found in the provided articles that align with the quantitative thresholds defined in the rubric for any of the KPIs related to Respect for Cultures & Communities. The articles primarily focus on the company's drug development pipeline, regulatory approvals, and financial arrangements, without detailing community engagement, cultural sensitivity, or social responsibility initiatives. Therefore, no assessment can be made against the given rubric.

Safe & Smart Tech

0

Lipocine Inc. reports no incidents of unauthorized data use.

1
The company states it does not sell or release mailing lists or user information.
2
Users can voluntarily submit personally identifiable information and have rights to request information and to have their data deleted.
3

Zero Waste & Sustainable Products

0

The provided articles focus on Lipocine Inc.'s financial performance, drug development pipeline, and regulatory milestones, such as FDA approval for TLANDO and fast track designation for LPCN 1148.

1
However, no specific data or information is available regarding the company's waste management practices, product recyclability, packaging sustainability, or any other initiatives related to zero waste or sustainable products.
2
Therefore, no KPIs under this value can be scored.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.