MASHINIi

Connect Biopharma Holdings Limited.

CNTB.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products

Connect Biopharma Holdings Limited is a global clinical-stage biopharmaceutical company dedicated to discovering and developing innovative therapies for the treatment of chronic inflammatory diseases with unmet medical needs. The company focuses on developing differentiated therapies to improve the ...Show More

Ethical Profile

Mixed.

Connect Biopharma Holdings Limited (CNTB.US) presents a mixed ethical profile. The company is actively developing therapies for inflammatory diseases, with its lead product, rademikibart, demonstrating positive Phase 2 trial results for asthma, including improved lung function. This therapy is now advancing to Phase 3 trials following FDA agreement, backed by $51.9 million in R&D expenses in 2023. However, the biopharmaceutical sector's reliance on animal testing for drug development raises concerns regarding animal welfare, a practice Connect Biopharma's activities are linked to. While the FDA is encouraging alternatives, specific details on CNTB.US's animal testing policies or investment in non-animal methods are not available. Information regarding fair pay, environmental impact, and supply chain ethics is also largely unavailable.

Value Scores

Better Health for All20
-100100
Fair Money & Economic Opportunity0
-100100
Fair Pay & Worker Respect0
-100100
Fair Trade & Ethical Sourcing0
-100100
Honest & Fair Business0
-100100
Kind to Animals0
-100100
No War, No Weapons0
-100100
Planet-Friendly Business0
-100100
Respect for Cultures & Communities0
-100100
Safe & Smart Tech0
-100100
Zero Waste & Sustainable Products0
-100100

Better Health for All

20

Connect Biopharma is a clinical-stage biopharmaceutical company focused on developing therapies for chronic inflammatory diseases. Its entire pipeline, including rademikibart for atopic dermatitis and asthma, CBP-307 for ulcerative colitis, and CBP-174 for chronic pruritus, aims to deliver substantial health benefits.

1
Rademikibart has shown positive Phase 2b results, with significant EASI reduction in atopic dermatitis and improved lung function and reduced asthma exacerbations.
2
The FDA has agreed to advance rademikibart into Phase 3 trials, and an NDA for rademikibart was submitted in China.
3
As a clinical-stage company, it has zero harmful products since its inception. In clinical trials, rademikibart and icanbelimod were generally well-tolerated, with most adverse events being mild or moderate and no serious treatment-emergent adverse events related to treatment reported for rademikibart.
4
The company reported R&D expenses of $51.9 million in 2023.
5
The company conducts global clinical trials and has published positive data from a global Phase 2 trial of rademikibart.
6

Fair Money & Economic Opportunity

0

Connect Biopharma Holdings Limited is a biopharmaceutical company focused on developing therapies for chronic inflammatory diseases.

1
Its core business does not involve lending, insuring, moving, or storing money for consumers.
2
Therefore, all KPIs related to fair money and economic opportunity, which are designed for financial service providers, are not applicable to the company's operations. The company does not offer consumer credit products, manage customer finance data, or operate financial service access points.
3

Fair Pay & Worker Respect

0

No specific, quantitative data for Connect Biopharma (CNTB.US) was found across any of the provided articles for the 'Fair Pay & Worker Respect' KPIs. Information regarding CEO compensation ratios was presented for the broader pharmaceutical or biotech industry, or for other specific companies, but not for CNTB.US directly.

1
Employee turnover rates were also presented for the broader pharmaceutical or biotech industry, or for other specific companies, but not for CNTB.US directly.
2

Fair Trade & Ethical Sourcing

0

No specific, quantitative evidence was found in the provided articles to assess Connect Biopharma Holdings Limited against any of the Fair Trade & Ethical Sourcing KPIs. The articles discuss general industry challenges in sourcing pharmaceutical ingredients, the importance of supply chain management, and relevant third-party assessment bodies, but they do not provide company-specific data on fair trade certifications, audit frequency, forced/child labor incidents, traceability, remediation speed, ethical clause coverage, materials risk index, or supplier diversity spend for CNTB.US.

Honest & Fair Business

0

No specific, concrete data points or metrics relevant to any of the 'Honest & Fair Business' KPIs were found in the provided articles. The articles explicitly state the absence of information regarding regulatory fines, transparency benchmarks, whistleblower policies, financial restatements, audit coverage, ESG controversies, complaint resolution times, board conflicts of interest, anti-corruption policies, or third-party verification of ethical claims.

1

Kind to Animals

0

No specific evidence was found in the provided articles regarding Connect Biopharma Holdings Limited's practices or policies related to animal welfare. The articles primarily discuss general trends in alternative testing methods, regulatory changes by the FDA and EPA, and the practices of other companies like AstraZeneca, without providing any concrete data points for CNTB.US across any of the specified KPIs.

No War, No Weapons

0

No specific information or data points regarding Connect Biopharma Holdings Limited's association with arms manufacturing, military contracts, conflict facilitation, or related ethical practices were found in the provided articles. The articles discuss general U.S. export controls and investment restrictions on biotechnology equipment due to dual-use potential, but they do not provide any company-specific details for CNTB.US, nor do they indicate that CNTB.US is involved in any defense-related activities or has any exposure to dual-use technologies with military applications.

1

Planet-Friendly Business

0

The provided articles discuss general sustainability trends and challenges within the biopharmaceutical industry, including efforts to reduce carbon footprints, manage plastic waste, and improve supply chain transparency. However, none of the articles provide specific, concrete data points or actions directly attributable to Connect Biopharma Holdings Limited (CNTB.US) for any of the Planet-Friendly Business KPIs.

1
Therefore, no KPIs can be scored based on the evidence provided.

Respect for Cultures & Communities

0

No specific, concrete data points for Connect Biopharma Holdings Limited (CNTB.US) were found in the provided articles regarding its respect for cultures and communities.

1
The articles discuss general diversity, equity, and inclusion (DEI) trends within the biotechnology and biopharmaceutical industries, and hiring practices, but do not offer company-specific evidence for any of the defined KPIs.
2

Safe & Smart Tech

0

No evidence available to assess Connect Biopharma Holdings Limited on Safe & Smart Tech.

Zero Waste & Sustainable Products

0

The provided articles discuss general sustainability trends in the biopharmaceutical industry and highlight initiatives by other companies like Cytiva

1
and Parcel Health.
2
However, none of the articles contain specific, quantitative data or verifiable actions directly attributable to CNTB.US regarding waste diversion rates, product recyclability, packaging sustainability, recycled content, single-use plastic reduction, take-back programs, circular design principles, waste reduction initiatives, hazardous waste management, product durability, repairability scores, waste audit frequency, zero-waste certifications, waste disposal violations, material efficiency, packaging-to-product ratio, waste reduction targets, supplier waste requirements, or customer waste education.

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AI-generated analysis based on publicly available data. Not financial advice. Ratings are expressions of opinion derived from automated models and may contain inaccuracies. See our Risk Disclosure for full details.