Apogee Therapeutics, Inc..
APGE.US | Manufacture of pharmaceuticals, medicinal chemical and botanical products
Apogee Therapeutics, Inc. is a biotechnology company focused on developing novel biologics for the treatment of inflammatory and immunological (I&I) diseases. They are engineering monoclonal antibody therapeutics to address unmet needs in I&I, with a focus on diseases with high unmet need and valida...Show More
Better Health for All
20
Apogee Therapeutics is entirely focused on developing novel therapies for inflammatory and immunological diseases, with its entire business devoted to health improvement.
1
Its lead candidate, APG777, demonstrated a 71.0% decrease in EASI from baseline and a 66.9% EASI-75 response rate in a Phase 2 trial for moderate-to-severe atopic dermatitis, which is noted as the highest reported EASI-75 response rate in any global biologic trial in AD to date.
2
The company has no revenue from products with direct negative health outcomes. APG777 was well tolerated in trials, with serious treatment-emergent adverse events (TEAEs) at 1.2% for treated patients versus 2.4% for placebo, and a low discontinuation rate of 2.4% due to AEs.
3
The company reported $167.9 million in R&D expenses in 2024 and $46.4 million in Q1 2025, indicating substantial investment in health innovation.
4
Apogee anticipates initiating a Phase 1 clinical trial of APG777 in healthy volunteers and has conducted a randomized, placebo-controlled Phase 2 APEX clinical trial.
5
However, the company explicitly states that its forward-looking statements are subject to risks and uncertainties detailed in its SEC filings, which could be interpreted as a limitation on transparency.
6
Fair Money & Economic Opportunity
0
No evidence available to assess Apogee Therapeutics, Inc. on Fair Money & Economic Opportunity.
Fair Pay & Worker Respect
0
No specific, quantitative data points were found across the provided articles to assess Apogee Therapeutics, Inc. against the 'Fair Pay & Worker Respect' KPIs. Information regarding living wage coverage, CEO to median employee pay ratio, collective bargaining share, safety incident rate, pay equity ratio, worker engagement score, turnover rate, labor violation incidents, insecure contract share, or health insurance coverage was explicitly stated as 'Not applicable' or 'No data available' in the articles.
1
Mentions of potential conflicts of interest or material non-public information concerns are not substantiated labor law violations.
2
Fair Trade & Ethical Sourcing
0
No specific, concrete data points were found in the provided articles to assess Apogee Therapeutics, Inc. against the 'Fair Trade & Ethical Sourcing' value. While the company has a Supplier Code of Ethics (July 2025) that outlines prohibitions against forced and child labor, and a Code of Business Conduct and Ethics (September 2025) that applies to collaborators,
1
there is no quantitative evidence on the percentage of suppliers covered by these clauses, nor any data on audit frequency, traceability, or substantiated incidents of labor violations. Therefore, no KPIs can be scored.
Honest & Fair Business
-40
Apogee Therapeutics provides a confidential and anonymous hotline, available 24/7/365, hosted by a third-party provider, along with a secure web form.
1
However, there is no evidence provided regarding independent investigation processes for reports received through this channel.
2
Kind to Animals
0
No information was found in the provided articles regarding Apogee Therapeutics, Inc.'s (APGE.US) specific practices, policies, or performance related to animal welfare, animal testing, or ethical sourcing. While one article mentions certifications for conducting laboratory animal experiments and the use of animal models (zebrafish, murine, humanized mouse models) in research by individuals, it does not provide company-specific data on animal testing volume, policies, or investments in animal-free alternatives for APGE.US.
1
Other articles discuss general FDA initiatives to reduce animal testing and the availability of alternative methods, but do not link these directly to APGE.US's actions or commitments.
2
No War, No Weapons
0
The provided articles, including those from Apogee Therapeutics' own website, explicitly state that they do not contain any data relevant to the company's involvement in arms or defense contracts, dual-use technologies, peacebuilding initiatives, or any other conflict-related issues.
1
Therefore, no specific, concrete data points are available to score any of the KPIs against the 'No War, No Weapons' value.
Planet-Friendly Business
0
No evidence available to assess Apogee Therapeutics, Inc. on Planet-Friendly Business.
Respect for Cultures & Communities
0
No specific, concrete data points were found in the provided articles for Apogee Therapeutics, Inc. (APGE.US) that are relevant to the KPIs under the 'Respect for Cultures & Communities' value.
1
The articles primarily focus on corporate governance, clinical trial results, and internal codes of conduct, without detailing community engagement, cultural impact assessments, or related initiatives. Information pertaining to 'Apogee Instruments' or 'apogeecorp.com' was excluded as it refers to different entities than Apogee Therapeutics, Inc.
Safe & Smart Tech
0
Apogee Therapeutics has reported no specific data breaches or incidents in the last fiscal year.
1
The company performs regular vulnerability scans.
2
All Apogee Representatives are required to complete annual training on the Code of Business Conduct and Ethics, which includes security aspects like not sharing passwords, but there is no mention of measuring its effectiveness.
3
The company prohibits the use of confidential information for personal benefit and states that access to such information is on a "need-to-know" basis.
4
Apogee is committed to compliance with applicable privacy laws such as CCPA, GDPR, and HIPAA.
5
The company respects the privacy of employees and patients in clinical trials.
6
No specific incidents of unauthorized data use have been reported.
7
Zero Waste & Sustainable Products
0
No specific, concrete evidence was found in the provided articles to assess Apogee Therapeutics, Inc. against any of the 'Zero Waste & Sustainable Products' KPIs. The articles primarily consist of financial reports, a code of conduct with general commitments, and market overviews for the pharmaceutical packaging industry. , which contained specific data points, appears to refer to Apogee Corporation (APOG), a different entity, based on the products (aluminum, glass, paint) and facilities mentioned, which do not align with Apogee Therapeutics' (APGE.US) business as a biotechnology company developing biologics.
1
Therefore, no measurable data points for waste diversion rates, product recyclability, packaging sustainability, or other relevant metrics for APGE.US could be identified.